'Digital health' is the latest umbrella term to encompass technical innovation in the healthcare landscape. Digital health includes any technologies used to support diagnosis, prevention, treatment, adherence, lifestyle, and most importantly, patient engagement. The development of these solutions has been evolving for years, but their use in patient care and clinical research accelerated during the pandemic, particularly for cancer patients, who are highly vulnerable to COVID-19 morbidity and mortality. This white paper discusses individualized digital health, Digital Health in clinical trials, and how COVID-19 is accelerating the pace of oncology research.